Sunday, July 25, 2010

Do you have people with fluid retention who are not responding as well as they could to Frusid?

At a recent Medication Adminstration Training Session for Caregivers, Gigi Lim, Senior Lecturer at Auckland University was saying that if Frusid is given after food, the medication action may be delayed (See below Pharmcokinetics for Frusid from Medsafe Website)

So if you have people who are not responding as well as expected to Frusid Medication administration time may the problem. Discuss with your doctor and Pharmacist and see if shifting the administration time could make a difference.

Pharmacokinetics
Approximately 60 to 70% of an oral dose of frusemide is absorbed. Peak plasma concentrations occur 60 minutes after oral administration and 30 minutes after intramuscular injection. They increase with increasing dose. Administration after food apparently delays absorption producing lower but more persistent blood concentrations.

Full Fact Data Sheet can be viewed at http://www.medsafe.govt.nz/profs/datasheet/f/Frusidtabinj.htm

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